What is it about?
rClCa2 is associated with epidermal differentiation, we found that it was strongly down-regulated by exposure to the main component of solar radiation UVb, this might be one of the way sun exposure leads to skin cancer
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Why is it important?
rClCA2 is a differentiation associated molecule and its downregulation could lead to cancer Most importantly this gene is associated with tumor-suppressor effect
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This page is a summary of: rClca2is associated with epidermal differentiation and is strongly downregulated by ultraviolet radiation, British Journal of Dermatology, July 2014, Oxford University Press (OUP),
DOI: 10.1111/bjd.13038.
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