What is it about?
Quantitative HBsAg may be useful to predict the clearance of HDV-RNA in during Peg-IFN therapy.
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Why is it important?
HBsAg decline at month 6 of therapy and HDV-RNA discriminated responders to treatment from non - responders. A threshold of 0.105 log reduction of HBsAg associated with 1.610 log reduction of HDV-RNA from baseline to month 6 predicted the clearance of this marker
Perspectives
Both quantitative HBsAg and HDV-RNA may provide a guide to prolong or stop therapy
Grazia Anna Niro
Ospedale Casa Sollievo della Sofferenza
Read the Original
This page is a summary of: HBsAg kinetics in chronic hepatitis D during interferon therapy: on-treatment prediction of response, Alimentary Pharmacology & Therapeutics, July 2016, Wiley,
DOI: 10.1111/apt.13734.
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