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Why is it important?
This work demonstrates that it is possible to inhibit voiding, even when the bladder was full, by electrical stimulation within the midbrain's micturition control centre. This finding provides proof of concept for further investigations into the possibility of developing this procedure to treat urinary urge incontinence in humans
Perspectives
The use of neuromodulation to alter the excitability of nerve circuits that control many different aspects of body and brain function is a growing field. This paper, which shows the ability of deep brain stimulation (DBS) in the midbrain can produce a rapid onset temporary block of micturition, illustrates the potential of DBS to control urinary coontinence
Dr Thelma A Lovick
University of Bristol
Read the Original
This page is a summary of: Effect of electrical vs. chemical deep brain stimulation at midbrain sites on micturition in anaesthetized rats, Acta Physiologica, April 2015, Wiley,
DOI: 10.1111/apha.12491.
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