What is it about?
Numerous environmental factors are known to trigger type 1 diabetes. This study aimed to determine whether there is an association between influenza and new-onset type 1 diabetes. Although only patients with type 1 diabetes were included, in the adjusted analysis, individuals had a 1·3-fold (95% confidence interval: 1·15–1·46) higher risk of developing type 1 diabetes within 180 days after an influenza diagnosis than at other times. The sensitivity analyses confirmed the robustness of this finding.
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Why is it important?
The risk of new-onset type 1 diabetes increased after influenza was diagnosed in this Japanese population-based cohort. using administrative claims database. These results, which must be confirmed in other populations, suggest that influenza virus infection may be a causal factor in new-onset type 1 diabetes. The molecular mechanisms underlying the potential etiological relationship between influenza and type 1 diabetes requires should be evaluated further.
Perspectives
Writing this article was a great pleasure as it has co-authors with whom I have had standing collaborations. More than anything else, and if nothing else, I hope you find this article thought-provoking.
Yuichi Nishioka
Nara Medical University
Read the Original
This page is a summary of: Association between influenza and the incidence rate of new‐onset type 1 diabetes in Japan, Journal of Diabetes Investigation, April 2021, Wiley,
DOI: 10.1111/jdi.13540.
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