Crystal structures of two new 3-(2-chloroethyl)-r(2),c(6)-diarylpiperidin-4-ones

What is it about?

The syntheses and crystal structures of 3-(2-chloroethyl)-r-2,c-6-diphenylpiperidin- 4-one, C19H20ClNO, (I), and 3-(2-chloroethyl)-r-2,c-6-bis(4-fluorophenyl) piperidin-4-one, C19H18ClF2NO, (II), are described. The piperidone ring adopts a chair conformation in (I), whereas a slightly distorted chair conformation is formed in (II). The dihedral angle between the mean plane of the phenyl rings is 59.1 (1) in (I) and 76.1 (1) in (II). The crystal packing features weak intermolecular N—H  O hydrogen bonds in each structure.

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