What is it about?
The reaction between 2-amino-6-nitrobenzothiazole and sulfosalicylic acid produces an organic salt. The cation is formed when 2-amino-6-nitrobenzothiazole is protonated at the intracyclic nitrogen, while the anion is formed when sulfosalicylic acid loses a hydrogen atom from its sulfonic acid group.
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Why is it important?
The organic salt formed from two pharmacophores can be considered a hybrid molecule, exhibiting the antimicrobial activity of each pharmacophore individually.
Perspectives
Carry out several bioassays on the hybrid molecule
Joseph Tsemeugne
aLaboratory of Natural Products and Applied Organic Synthesis (LANAPOS), Department of Organic Chemistry, Faculty of Science, University of Yaounde I, P.O. Box 812 Yaounde, Republic of Cameroon;
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This page is a summary of: 2-Amino-6-nitro-1,3-benzothiazol-3-ium 3-carboxy-4-hydroxybenzene-1-sulfonate, IUCrData, May 2025, International Union of Crystallography,
DOI: 10.1107/s241431462500478x.
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