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Our knowledge of medicine and biochemistry is largely informed by our knowledge of the intricate 3D shapes proteins take on that allow them to function. However, out knowledge-base of these protein shapes has many errors in it that can cause mistakes in later scientific studies. This work describes how citizen scientists playing the biochemistry video game Foldit are correcting these errors to improve our public knowledgebase of protein structure.

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This page is a summary of: Reconstructing biological molecules with help from video gamers, Acta Crystallographica Section D Structural Biology, October 2025, International Union of Crystallography,
DOI: 10.1107/s2059798325008149.
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