What is it about?
Calibration standards are necessary for verifying instrumentation readiness and workflows. Instead of trying to make one biomacromolecule a one-size-fits-all standard, creating optimized mixtures for relevant properties can be more robust and reliable.
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Why is it important?
As researchers are making use of structural science tools, such as cryoEM, they need standard operating procedures to validate the technologies they are using.
Perspectives
Scientists like to try to reduce problems to make studies simpler and easier to conduct. But sometimes it is necessary to be able to interpret a combination of samples or more complex systems. The purpose of this study is to start making use of mixtures in cryoEM.
Edward Eng
New York Structural Biology Center
Read the Original
This page is a summary of: Multi-species cryoEM calibration and workflow verification standard, Acta Crystallographica Section F Structural Biology Communications, October 2024, International Union of Crystallography,
DOI: 10.1107/s2053230x24010318.
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