What is it about?
500 million years ago, a spineless marine creature experienced two successive DNA doublings – triggering evolution of the backboned animals. This paper shows how these ancient DNA doublings boosted communication systems, so that human cells are better at integrating information than the smartest smartphones. The downside is that communication breakdowns cause diabetes, cancer and neurological disorders. Amazingly, what happened so long ago still affects the life and diseases of modern humans.
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Why is it important?
500 million years ago, a spineless marine creature experienced two successive DNA doublings – triggering evolution of the backboned animals. This paper shows how these ancient DNA doublings boosted communication systems, so that human cells are better at integrating information than the smartest smartphones. The downside is that communication breakdowns cause diabetes, cancer and neurological disorders. Amazingly, what happened so long ago still affects the life and diseases of modern humans.
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This page is a summary of: Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates, Open Biology, July 2012, Royal Society Publishing,
DOI: 10.1098/rsob.120103.
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