What is it about?
We report about a person who had progressive word retrieval difficulty (more so during confrontation naming) without explicit loss of semantic knowledge or phonological processing difficulty. We propose that a breakdown in visual-lexical interface was the likely culprit. She additionally developed Gerstmann syndrome. This individual was dealing with an atypical form of Alzheimer's disease.
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Why is it important?
In the context of Alzheimer disease , patients may present with symptoms and signs that do not exclusively fit into one of the existing phenotypic categories, which often delays timely diagnosis and initiation of services to optimize patient (and family) awareness and coping.
Perspectives
A typical manifestations of Alzheimer's disease need to be researched and published to increase awareness among health care providers.
Dr. Adithya Chandregowda
Nova Southeastern University
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This page is a summary of: A Case of Atypical Alzheimer Disease With Clinical Manifestation That Straddled the Boundary Between Primary Progressive Aphasia and Posterior Cortical Atrophy, The Neurologist, August 2022, Wolters Kluwer Health,
DOI: 10.1097/nrl.0000000000000458.
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