What is it about?
A population sample of 96 cases of VTE, without strong or moderate inherited or noninherited predisposing factors, and 148 healthy controls were analyzed for variants in genes ABO (rs2519093; rs8176719), F11 (rs2036914; rs2289252) and FGG (rs2066865).
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Why is it important?
Our data suggest that SNPs ABO rs8176719 and FGG rs2066865 may contribute individually to the VTE susceptibility in the Portuguese population.
Perspectives
A genetic risk score combining the VTE-associated FGG and ABO alleles improved the risk prediction of VTE.
Dr Teresa Fidalgo
Read the Original
This page is a summary of: Venous thromboembolism risk associated with ABO, F11 and FGG loci, Blood Coagulation & Fibrinolysis, July 2018, Wolters Kluwer Health,
DOI: 10.1097/mbc.0000000000000753.
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