Traits associated with central pain augmentation in the Knee Pain In the Community (KPIC) cohort

  • Kehinde Akin-Akinyosoye, Nadia Frowd, Laura Marshall, Joanne Stocks, Gwen S. Fernandes, Ana Valdes, Daniel F. McWilliams, Weiya Zhang, Michael Doherty, Eamonn Ferguson, David A. Walsh
  • Pain, June 2018, Wolters Kluwer Health
  • DOI: 10.1097/j.pain.0000000000001183

Creating a tool to improve personalisation of osteoarthritis knee pain treatment.

What is it about?

We found that 8 characteristics of osteoarthritis knee pain were related the central nervous system (brain or spinal cord). These characteristics were anxiety; depression; other painful areas; how one thinks about pain; how pain affects attention to a task; sleep disturbance; fatigue; and pain that feels tingly or electrical in nature.

Why is it important?

Through selecting 8 questions representing these characteristics we have created a new questionnaire to help identify people whose pain is driven by the central nervous system. Clinicians can use this questionnaire to help identify individuals whose central pain mechanisms play a significant role in driving pain. It will help determine whether current or new treatments that target central pain mechanisms, might improve a specific individual’s knee pain.

Perspectives

Dr Daniel McWilliams
University of Nottingham

For large scale surveys (of big populations or large studies of people), this questionnaire will be very useful for helping researchers work out what mechanisms might be causing pain.

Read Publication

http://dx.doi.org/10.1097/j.pain.0000000000001183

The following have contributed to this page: Dr Joanne Stocks and Dr Daniel McWilliams