What is it about?
Sickle cell disease (SCD) affects nearly 100,000 people in the United States of America and the sickle gene is present in approximately 8% of black Americans. Among Africans, the prevalence of sickle cell trait (heterozygosity) is as high as 30%. While SCD occurs among varying racial and ethnic groups, it is more commonly prevalent in individuals of African or African-American descent.
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Why is it important?
This inherited blood disorder causes varying symptoms and complications among affected children and adults and early diagnosis and treatment are essential to help reduce mortality rates. Because there is no cure for SCD, management is vital to survival.
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This page is a summary of: Current modalities of sickle cell disease management, Blood Science, August 2020, Wolters Kluwer Health,
DOI: 10.1097/bs9.0000000000000056.
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