What is it about?
This was the first evidence ever published of oxidative stress being involved in Parkinson's disease. It showed that Lewy Bodies and Pale bodies (neuropathological markers of Parkinson's disease) had abnormal levels of heat shock proteins and other abnormal substances induced by oxidative stress.
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Why is it important?
The study demonstrate a pathway responsible for cell death in Parkinson's disease. It offers avenues and possibilities for prevention and treatment.
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This page is a summary of: IMUNOHISTOCHEMICAL EVIDENCE OF OXIDATIVE STRESS IN PARKINSONʼS DISEASE (PD), Journal of Neuropathology & Experimental Neurology, May 1996, Oxford University Press (OUP),
DOI: 10.1097/00005072-199605000-00127.
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