Publication
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
Jesper B. Bramsen, Maria B. Laursen, Anne F. Nielsen, Thomas B. Hansen, Claus Bus, Niels Langkjær, B. Ravindra Babu, Torben Højland, Mikhail Abramov, Arthur Van Aerschot, Dalibor Odadzic, Romualdas Smicius, Jens Haas, Cordula Andree, Jharna Barman, Malgorzata Wenska, Puneet Srivastava, Chuanzheng Zhou, Dmytro Honcharenko, Simone Hess, Elke Müller, Georgii V. Bobkov, Sergey N. Mikhailov, Eugenio Fava, Thomas F. Meyer, Jyoti Chattopadhyaya, Marino Zerial, Joachim W. Engels, Piet Herdewijn, Jesper Wengel, Jørgen Kjems
Nucleic Acids Research, March 2009, Oxford University Press (OUP)
DOI: 10.1093/nar/gkp106