What is it about?
VAPPER is a tool that allows automated analysis of the variant antigen repertoires of the most prevalent livestock African trypanosomes, Trypanosoma congolense and Trypanosoma vivax. These profiles cam be made from genomic and transcriptomic short sequencing data and are shown as publication-ready figures. VAPPER is implemented in Python and can be installed to a local Galaxy instance.
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Why is it important?
By establishing two different, yet comparable methodologies, VAPPER is the first tool to allow large-scale analysis of African trypanosome variant antigens, large multi-copy gene families that are otherwise refractory to high-throughput analysis.
Read the Original
This page is a summary of: VAPPER: High-throughput variant antigen profiling in African trypanosomes of livestock, GigaScience, August 2019, Oxford University Press (OUP),
DOI: 10.1093/gigascience/giz091.
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