Progression of atherosclerosis

What is it about?

The study demonstrates that the progression of coronary atherosclerosis, measured as the degree of coronary artery calcification (CAC), seems to be inevitable ongoing. Risk fatcors play a minor role, as the expained variance reaches 80% modified by risk factors for about 1-2%. Therefore, CAC progression can be predicted based on a mathematical tool which we developed. An App - CAC prediction - is available as well as a window version.

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Why is it important?

CAC scoring for risk prediction has become a useful tool. Patients are treated with statines and other drugs in order to reduce the risk. That is evidence based strategy. But when CTs are repeated the physician and patient will be surprised to see that the degree of CAC has increased with no sign of attentuation. Our CAC prediction tool helps to explain the patient the process of atherosclerosis, which seem to be inevitable, genetically based, and thus progressive, but predictable