Dynamic CT perfusion measurement of myocardial blood flow in low-risk individuals

What is it about?

CT measurement of myocardial blood flow at stress and rest has not been previously documented individuals at low-risk of coronary artery disease. Without knowing measurements in low-risk or "normal" individuals, it is difficult to appreciate abnormal results. Low-risk patients were chosen on the basis of the Framingham risk score and a low Calcium Score. Rest & stress myocardial blood flow was documented, including values in different coronary artery territories.

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Why is it important?

1) Quantitation of myocardial blood flow is potentially important in accurate description the presence and severity of coronary artery disease. This paper establishes such values in low-risk individuals. 2) There was a significant difference in blood flow measurements compared to patients with established coronary artery disease. 3) The technique used a radiation dose-saving strategy of 80kV, reducing dose by 30% compared to previously established strategies using 100kV.