What is it about?
We hypothesized that hydrogel with different mechanical stiffness can provide a biomimetic mechanical environment that can modulate bone tissue growth and mineralization.
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Why is it important?
Since this system enhances and shortens the mineralization procedure compared with the conventional two-dimensional or three-dimensional cell culture system, this hydrogel system would be one of the unique models for better understanding the mineralized tissue development.
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This page is a summary of: Early Initiation of Endochondral Ossification of Mouse Femur Cultured in Hydrogel with Different Mechanical Stiffness, Tissue Engineering Part C Methods, June 2015, Mary Ann Liebert Inc,
DOI: 10.1089/ten.tec.2014.0475.
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