What is it about?

Collagen corneal cross-linking (CXL) is an invasive pharmacological treatment strategy used for corneal ectatic disorders and is currently the only treatment capable of halting the progression of the disease

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Why is it important?

Because of the variety of different protocols that are currently used, the results that are being reported are very variable, and could generate some confusion in relation to the true efficacy of the procedure. The aim of this review was to provide an overview of the aforementioned protocols that are designed to maintain the efficacy of CXL in halting the progression of the disease but avoiding the major limitations of the procedure.

Perspectives

Modified corneal crosslinking should be revisited, due to the lack of data about its real efficacy

MD Diego A. Valera-Cornejo
Vista Clinic

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This page is a summary of: Invasive Pharmacology Outcomes with Different Corneal Cross-Linking Protocols: A Review, Journal of Ocular Pharmacology and Therapeutics, November 2019, Mary Ann Liebert Inc,
DOI: 10.1089/jop.2018.0144.
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