Thrombin Inhibition: Preliminary Assessment of the Anticoagulant Potential of Turnera subulata.

What is it about?

Study evaluated the Turnera subulate leaf effect on the coagulation cascade and its possible side effects. Results indicate significant anticoagulant activity, probably due to polyphenols. No toxicity was observed in vitro and in vivo. T. subulata leaf active compounds exhibit therapeutic potential required to develop phytotherapeutic formulations to assist conventional anticoagulants in clinical treatments.

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Photo by Testalize.me on Unsplash

Photo by Testalize.me on Unsplash

Why is it important?

Results suggest direct and indirect thrombin inhibition as the main mechanism of action.

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