What is it about?

We herein present novel microfluidic channels for simultaneous high-throughput cell self-rotation using local circular streaming generated by ultrasonic wave excited bubble arrays.

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Why is it important?

Comparing with conventional approaches (e.g., mechanical contact based, dielectrophoresis, optical tweezers) of cell rotation, our device has multiple merits such as high throughput, low cost and simple fabrication procedure, and high compatibility for lab-on-chip integration.

Perspectives

The microfluidic channel is easy to be connected to other functional modules in series, which is a very competitive merit in integrated lab-on-chip systems. As the desire of high-throughput analysis of cells steadily increases, our acoustic streaming rotating platform is very promising in future application.

Professor Wenhui Wang
Tsinghua University

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This page is a summary of: High-throughput acoustofluidic microchannels for single cell rotation, Journal of Micromechanics and Microengineering, November 2021, Institute of Physics Publishing,
DOI: 10.1088/1361-6439/ac349e.
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