What is it about?

Due to their renewal and potency, umbilical cord blood (UCB) stem cells have the ability to proliferate and serve as an attractive alternative source for bone marrow transplantation. However, insufficient number of haematopoietic stem cells (HSCs) in UCB is still a major constraint in clinical applications.

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Why is it important?

In vitro expansion of stem cells on fibronectin (Fn)-coated poly-L-lactic acid (PLLA) scaffold can be a proper way to overcome this limitation.

Perspectives

The Fn-coated PLLA scaffold could be a suitable in vitro mimicry niche over a 2D system

maryam islami
Zanjan University of Medical Sciences

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This page is a summary of: In vitro expansion of CD 133+ cells derived from umbilical cord blood in poly-L-lactic acid (PLLA) scaffold coated with fibronectin and collagen, Artificial Cells Nanomedicine and Biotechnology, August 2017, Taylor & Francis,
DOI: 10.1080/21691401.2017.1358733.
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