What is it about?
Rab35 is an oncogenic Rab that just started to be related as such, we reviewed the different roles of this protein in different settings and proposed a possible role of Rab35 in Leukemia, based on the functions reported in lymphocytes and other immune cells
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Why is it important?
Leukemia similar to other Cancers has multiple factors that contribute to their development, knowing more of those factors could open new windows of opportunity for their diagnostic or treatment
Perspectives
We expect that this proposal will inspire new studies for Rab35 by other groups and those could complement our own studies that are under way
Dr. Genaro Patino-Lopez
Children's Hospital of Mexico
Read the Original
This page is a summary of: The role of the oncogenic Rab35 in cancer invasion, metastasis, and immune evasion, especially in leukemia, Small GTPases, May 2018, Taylor & Francis,
DOI: 10.1080/21541248.2018.1463895.
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