What is it about?
Drugs from Natural products have always played an important role in cancer treatment. Well known cancer drugs like etoposide and teniposide are derived from a natural product called Podophyllotoxin. Here in, we have planned some glycosyl triazoles linked to Podophyllotoxin and evaluated them for their anticancer activity. The primary results are encouraging and advanced studies are needed to validate the studies.
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This page is a summary of: Synthesis of podophyllotoxin-glycosyl triazoles via click protocol mediated by silver (I)-N-heterocyclic carbenes and their anticancer evaluation as topoisomerase-II inhibitors, Natural Product Research, June 2019, Taylor & Francis,
DOI: 10.1080/14786419.2019.1610958.
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