What is it about?
The differentiation of mesenchymal stem cells to adipocyte is halted by combination of ATRA and calcium.
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Why is it important?
Although, by some degree, both were shown that could hinder adipogenesis, the trend is a multi-factorial process that many nutrients and hormones can affect. Hence, applying some of these factors together may help the individuals to diminish the obesity in turn.
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This page is a summary of: Combined effect of retinoic acid and calcium on the in vitro differentiation of human adipose-derived stem cells to adipocytes, Archives of Physiology and Biochemistry, August 2017, Taylor & Francis,
DOI: 10.1080/13813455.2017.1367009.
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