What is it about?
Smooth muscle cell contraction in the airways is the principal therapeutic target in asthmatic subjects and its insufficient treatment is often a cause of uncontrolled disease. For this reason, research has focused on targeting smooth muscle activity with anticholinergic agents, including umeclidinium.
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Why is it important?
This review highlights the potential application of umeclidinium, a long acting muscarinic antagonist, as a novel therapeutic approach for patients with severe uncontrolled asthma, despite maximal therapy.
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This page is a summary of: Umeclidinium for the treatment of uncontrolled asthma, Expert Opinion on Investigational Drugs, April 2017, Taylor & Francis,
DOI: 10.1080/13543784.2017.1319472.
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