What is it about?
The study was to assess the cytotoxic effects of mixtures of oxysterols on two cell types associated with the atherosclerotic process, bovine aortic endothelial (BAE) cells and human monocytic U937 cells.
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Why is it important?
Results demonstrate interactive effects when oxysterols are studied as mixtures rather than single compounds in vitro.
Perspectives
This research helped to further the research on the mechanisms of oxysterol toxicity in two cell types associated with the atherosclerotic process, bovine aortic endothelial (BAE) cells and human monocytic U937 cells.
Aaron O'Sullivan
University College Dublin
Read the Original
This page is a summary of: Differential Effects of Mixtures of Cholesterol Oxidation Products on Bovine Aortic Endothelial Cells and Human Monocytic U937 Cells, International Journal of Toxicology, May 2005, SAGE Publications,
DOI: 10.1080/10915810590952951.
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