What is it about?
Graphene oxide (GO) was coated on a glass support through spin-coating technique. Then, Wharton’s Jelly mesenchymal stem cell (WJ-MSC) was confirmed by cell morphology, immunofluorescence of staining surface CD markers (CD105 and STRO-1), as well as differentiation into adipogenic and osteogenic lineages. In Day-1 of cell culture, WJ-MSC was able to adhere and growth on the GO substrate. Subsequent WJ-MSC cultured on the GO substrate has demonstrated promising cell viability for at least six days and this result is comparable to WJ-MSC grown on glass substrate (without GO).
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Why is it important?
This is the preliminary study of using spin-coated GO for culture human Wharton's jelly mesenchymal stem cell.
Perspectives
This study implies that GO substrate can be a suitable biomaterial for culturing WJ-MSC, which is an alternative mesenchymal stem cells source.
PERNG YANG PUAH
Universiti Malaysia Sabah
Read the Original
This page is a summary of: Spin-coated graphene oxide as a biomaterial for Wharton’s Jelly derived mesenchymal stem cell growth: a preliminary study, Materials Technology, September 2018, Taylor & Francis,
DOI: 10.1080/10667857.2018.1515300.
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