What is it about?
Gum diseases, scientific known as gingivitis and periodontitis, are caused by accumulation of hard and soft tissue deposits on the surface of the tooth and gums. These hard and soft tissue deposits contains millions of microorganisms that can enter the blood circulation and reach various organs in the body, including kidney. When the oral bacteria enter the kidney, they cause inflammation in the organs and cause the organ dysfunction. Our article highlights the key mechanisms by which the oral bacteria cause chronic kidney disease or end stage Kidney disease. The article highlights the role of gingivitis and periodontitis and the existing literature supporting the link between poor oral hygiene on in the development of pyelonephritis, renal stones, end stage renal disease, or renal failure.
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Why is it important?
The article is important as it explains how oral bacteria or microorganisms increase the inflammation in the renal tissue and leads to renal disorders. The article is timely as it proves that poor oral hygiene is a risk factor for kidney disorders. The paper is also important as it generates evidence that tooth cleaning and management of gun disease are important to control risk of renal dysfunction
Perspectives
The role of gum disease as a risk factor for systemic diseases is often ignored. The paper highlights the important mechanisms of how gingivitis and periodontitis can cause organ dysfunction and leads to renal diseases.
Dr. Aditi Chopra
Manipal College of Dental Sciences, Manipal
Read the Original
This page is a summary of: An update on possible pathogenic mechanisms of periodontal pathogens on renal dysfunction, Critical Reviews in Microbiology, February 2019, Taylor & Francis,
DOI: 10.1080/1040841x.2018.1553847.
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