What is it about?
Solid-state nuclear magnetic resonance spectroscopy combined with circular dichroism spectroscopy are used to study the interactions between the membrane-embedded segment of a neurotransmitter receptor with its surrounding lipids.
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Why is it important?
Lipids are shown to interact with the peptide. This suggests the possibility that the environmental lipids play a role in receptor function.
Perspectives
The work adds information on the modulation exerted by lipids on an important membrane protein.
Prof. Dr. Francisco J Barrantes
Lab. Molec. Neurobiology, BIOMED, UCA-CONICET
Read the Original
This page is a summary of: Structural and dynamic studies of the γ-M4 trans-membrane domain of the nicotinic acetylcholine receptor, Molecular Membrane Biology, January 2005, Taylor & Francis,
DOI: 10.1080/09687860500370653.
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