What is it about?

This study was aimed at investigating its interaction with other inflammatory mediators on mucosa surfaces, particularly the complement system.

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Why is it important?

Lysozyme is an ubiquitous enzyme found in most biological secretions and leukocytes.

Perspectives

Lysozyme has been shown in the present study, to inhibit the haemolytic activity of serum complement in a dose-dependent fashion, when tested within the levels present in normal and inflamed breast-milk samples, and other mucosal secretions. This represents a new anti-inflammatory action of lysozyme in relation to the serum complement, and the exact mode of the interaction need further studies.

Dr Michael O Ogundele
Mid Cheshire Hospitals NHS Foundation Trust Postgraduate Medical Centre

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This page is a summary of: A novel anti-inflammatory activity of lysozyme: modulation of serum complement activation, Mediators of Inflammation, January 1998, Hindawi Publishing Corporation,
DOI: 10.1080/09629359890893.
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