What is it about?
Methotrexate is an anti-metabolit agent which is used in treatment of skin conditions such as keratoacanthoma.We design a study to show whether intralesional methotrexate is effective in treatment of BCC
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Why is it important?
Yet,There was not any clinical trial about methotrexate effectiveness in treatment of BCC.since effect of methotrexate relates to mitotic rate,which is low in BCC;the study does not show any effect.
Perspectives
This study was about treatment of the most common skin neoplasm. Methotrexate is a safe and accessible therapy. So studying it’s effectiveness is worthy. The remarkable point is that although it is effective in conditions such as keratoacanthoma,results in treatment of BCC is not satisfactory.
Mahshid Ansari
Tehran University of Medical Sciences
Read the Original
This page is a summary of: Treatment of basal cell carcinoma: is intralesional methotrexate an option?, Journal of Dermatological Treatment, March 2018, Taylor & Francis,
DOI: 10.1080/09546634.2018.1451817.
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