What is it about?
We used the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire to evaluate neuropathic pain (NP) in 70 patients with breast cancer( BC). The patients were subjected to a 24-h Holter ECG monitorization to determine heart rate variability (HRV). According to the LANSS questionnaire, 18 (25.7%) of the patients were classified as NP (+). The cardiac sympathovagal activity were significantly affected in patients with NP than in patients without NP, whereas mean heart rate were found to be significantly higher in patients with NP . According to our findings, NP (+) patients with BC had increased cardiac sympathetic activity, which was suggested to be associated with increased cardiovascular morbidity and mortality.
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Why is it important?
This is the first study to show neuropathic pain is associated with changes in cardiac sympathovagal activity in breast cancer
Perspectives
According to our findings, NP (+) patients with BC had increased cardiac sympathetic activity, which was suggested to be associated with increased cardiovascular morbidity and mortality. This is very important for our clinical practice
sibel eyigor
Ege University Faculty of Medicine
Read the Original
This page is a summary of: Is neuropathic pain associated with cardiac sympathovagal activity changes in patients with breast cancer?, Neurological Research, February 2018, Taylor & Francis,
DOI: 10.1080/01616412.2018.1438225.
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