What is it about?
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are both serious chronic liver diseases worldwide. The cause of ALD is chronic alcoholism. NAFLD is a metabolic syndrome caused by excessive accumulation of triglycerides in liver cells without consumption of alcohol. Although the pathogeneses of these two liver diseases are different, the traditional treatments for these two liver diseases are mainly drug treatment. Drug treatment works quickly, but long-term use may produce side effects. Studies demonstrated that probiotics as a natural substance played a unique role in improving liver and intestinal health. This review overviews the pathogenesis of ALD and NAFLD, summarizes the health effects of probiotics in the treatment of ALD and NAFLD, and discusses the treating mechanisms of probiotics in order to provide a theoretical basis for future research.
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Why is it important?
Studies demonstrated that probiotics as a natural substance played a unique role in improving liver and intestinal health. This review overviews the pathogenesis of ALD and NAFLD, summarizes the health effects of probiotics in the treatment of ALD and NAFLD, and discusses the treating mechanisms of probiotics in order to provide a theoretical basis for future research.
Perspectives
Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations. This article also lead to rare disease groups contacting me and ultimately to a greater involvement in rare disease research.
Lactiplantibacillusplantarum LP4 alleviates alcoholic liver disease in C57BL/6 mice liu lingchong
Read the Original
This page is a summary of: Probiotics in treating with alcoholic liver disease and nonalcoholic fatty liver disease, Food Reviews International, September 2021, Taylor & Francis,
DOI: 10.1080/87559129.2021.1967380.
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