What is it about?
We show here that the second DNA polymerase essential for lagging strand replication is stimulated by SSB, mis-incorporate nucleotides at a high rate and is involved in DNA repair.
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Why is it important?
The bacterium B. subtilis, alike eukaryote cells, encodes two essential DNA polymerases. Here, we show that the polymerase dedicated to lagging strand synthesis is involved in DNA repair.
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This page is a summary of: Involvement of DnaE, the Second Replicative DNA Polymerase fromBacillus subtilis, in DNA Mutagenesis, Journal of Biological Chemistry, October 2003, American Society for Biochemistry & Molecular Biology (ASBMB),
DOI: 10.1074/jbc.m310719200.
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