What is it about?
We identified a discrete region within the α7 nicotinic receptor—a neuronal receptor widely recognized as a promising therapeutic target due to its roles in cognition, neuroprotection, and inflammation—from which cannabidiol modulates receptor activity.
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Why is it important?
Our findings help us understand how this family of receptors is regulated and open new possibilities for developing more precise and effective molecules with therapeutic potential.
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This page is a summary of: A cannabidiol-sensitive region involved in the allosteric modulation of the α7 nicotinic receptor, Proceedings of the National Academy of Sciences, June 2026, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2535398123.
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