What is it about?
Glutaraldehyde is the gold standard for the production of biological aortic valve prostheses containing xenogenic tissue like bovine pericardium. But treatment with glutaraldehyde causes early calcification and deterioration of bioprostheses. We tested the potential of new pretreatment for bioprosthetic materials for cardiac surgery. What's more, we share large original #bioimaging #histology data + #REMBI annotations in the faculty's #OMERO instance.
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Why is it important?
We show biocompatibility and low calcification potential suggesting the presented treatment protocol as promising candidate to develop cutting-edge cardiovascular– and valvular biomaterials in reconstructive surgery.
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This page is a summary of: In vivo application of a glutaraldehyde-free, UVA/riboflavin cross-linked bovine pericardium confirms suitability for cardiovascular substitutes, APL Materials, January 2024, American Institute of Physics,
DOI: 10.1063/5.0182672.
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