What is it about?
In this paper, a two-stage (micropore filtration and immuno-MB capture) microfluidic integrated chip for coarse-to-fine CTC isolation from whole blood is reported.
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Why is it important?
Isolation of rare circulating tumor cells (CTCs) from blood is critical for downstream analysis, which is important in cancer related research, diagnosis, and medicine. There are continuing efforts to increase CTC isolation efficiency and purity in microfluidics.
Perspectives
We envision that this platform provides a new solution to CTC isolation with the capability of incorporating additional on-chip cell manipulation and analysis modules.
Professor Wenhui Wang
Tsinghua University
Read the Original
This page is a summary of: On-chip circulating tumor cells isolation based on membrane filtration and immuno-magnetic bead clump capture, Nanotechnology and Precision Engineering, February 2022, American Institute of Physics,
DOI: 10.1063/10.0009560.
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