Hollow Microfiber Enzymatic Bioreactor

What is it about?

In this article, the authors present the fabrication of an enzyme-entrapped alginate hollow fiber using a microfluidic device. Further use of enzyme-entrapped alginate hollow fibers as a biocatalytic microchemical reactor for chemical synthesis is also deliberated in this article. To ensure that there is no enzyme leaching from the fiber, fiber surfaces were coated with chitosan.

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Why is it important?

A very efficient way of creating a bioreactor using biopolymer hollow microfiber which can be embedded in PDMS for continuous and long term use without losing the enzyme activity. Enzyme entrapped in such a system has done impressive thermal stability also.