The enigma of Atg9 vesicles in autophagy

What is it about?

Macroautophagy is an intracellular degradation system that involves the de novo formation of membrane structures called autophagosomes. In this review, the current understanding and potential mechanisms by which membrane trafficking participates in macroautophagy are described, with a focus on the enigma of the membrane protein Atg9, for which the proximal mechanisms determining its movement are disputable, despite its key role in autophagosome formation.

Featured Image