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We developed a new building block for a protein- and cell-repellant self-assembled monolayer (SAM) from 2-methacryloyloxyethyl phosphorylcholine (MPC) via a simple Michael-type addition to one mercapto group in alkanedithiol. The thiolated MPC can enable functionalization of a noble metal electrode to minimize noise signal in biosensing.
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This page is a summary of: Thiolated 2-methacryloyloxyethyl phosphorylcholine for an antifouling biosensor platform, Chemical Communications, January 2013, Royal Society of Chemistry,
DOI: 10.1039/c3cc44357d.
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