What is it about?

this new compound represent an innovative quinoxaline cavitand derivative, able to act as photodynamic compound

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Why is it important?

The fullerene-quinoxaline conjugate exhibits photoinduced DNA-cleaving activity, as confirmed by preliminary photocleavage experiments carried out with a pBR322 supercoiled plasmid.

Perspectives

The results will encourage the undertaking of further studies directed at gaining insights into the binding mode and towards clarifying the molecular mechanism of DNA photodamage.

Dr Giuseppe Trusso Sfrazzetto
University of Catania

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This page is a summary of: Synthesis and photophysics of a fullerene-triquinoxaline ensemble, New Journal of Chemistry, January 2010, Royal Society of Chemistry,
DOI: 10.1039/c0nj00481b.
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