What is it about?
The C–C bond formation between ketone and alcohol was promoted by Pd complex with N-heterocyclic carbene (NHC) ligands. The reaction involves the cleavage of C–H and O–H bonds of the alcohol that gives the aldehyde, followed by aldol condensation to give the alpha, beta-unsaturated ketone and subsequent hydrogenation of the resulting alpha, beta-olefin.
Featured Image
Read the Original
This page is a summary of: Cross-coupling reaction of alcohols for carbon–carbon bond formation using pincer-type NHC/palladium catalysts, Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry,
DOI: 10.1039/b914618k.
You can read the full text:
Contributors
The following have contributed to this page
