What is it about?

This report is about cell microscopy using a well-known electrochemical reaction that generates visible light: the phenomenon is called electrochemiluminescence (ECL) . The cells are imaged at the surface of a conducting electrode where the energy to trigger the ECL reaction is provided by the application of a potential and an external light stimulus. In brief, we use an incident and non-visible infrared light that excites a semiconductor electrode.

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Why is it important?

Firstly, the results show that this approach allows a decrease in the overpotential required to trigger the reaction at the electrode. Indeed, electrochemiluminescence usually requires high potentials. In addition, the incident infrared light brings a new dimension of control of the reaction, so of the imaging. Finally, the semiconductor involved, previously studied by our group, is very stable and the electrogenerated light is very intense.

Perspectives

This technique should find promising applications to image and to study single photoactive nanoparticles and biological entities.

Julie Descamps
Bordeaux INP

Read the Original

This page is a summary of: Infrared Photoinduced Electrochemiluminescence Microscopy of Single Cells, Chemical Science, January 2023, Royal Society of Chemistry,
DOI: 10.1039/d3sc05983a.
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