What is it about?
In this work we report on a bubble-free and clogging-free microfluidic particle separation platform with high throughput. The platform features with an integrated bidirectional micropump, a hydrophilic microporous filtration membrane and a hydrophobic porous degassing membrane.
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Why is it important?
Microfiltration is a compelling method to separate particles based on their distinct size and deformability. However, this approach is prone to clogging after processing a certain number of particles and forming bubbles in the separation procedure, which often leads to malfunctioning of devices.
Perspectives
The particle separation platform in virtues of bubble-free, clogging-free and multi-filtration presents an appealing and ingenious alternative for the enrichment of target particles based on size and deformability, holding a great promise for point-of-care pretreatment.
Professor Wenhui Wang
Tsinghua University
Read the Original
This page is a summary of: A bubble- and clogging-free microfluidic particle separation platform with multi-filtration, Lab on a Chip, January 2016, Royal Society of Chemistry,
DOI: 10.1039/c6lc01113f.
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