What is it about?

It is the first paper to identify haplotypes associated with increased sensitivity to CoCr metal debris. The paper describes the evidence on which the commercially available test "Orthotype" was developed. The initial phase of this work was awarded the British Hip Society Translational Research award in 2019. The published article represents a five year piece of work involving centres in the UK, USA and Australia.

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This page is a summary of: The influence of HLA genotype on the development of metal hypersensitivity following joint replacement, Communications Medicine, June 2022, Springer Science + Business Media,
DOI: 10.1038/s43856-022-00137-0.
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