What is it about?
Lymphocytes are essential part of the adaptive immune response, although much is known of the activation mechanisms, we still have a lot to learn, using published databases we explored new molecules that could be important for the early activation events that will lead to a complete T cell response.
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Why is it important?
Immune therapy is a burgeoning field and although incredible success has been reached for some diseases we still have many open questions, for example why some patients don´t respond well?, why is there clones that escape from the therapy?, etc., knowing more details of the productive immune cell activation could help to resolve some of those problems.
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This page is a summary of: Identification of potential new T cell activation molecules: a Bioinformatic Approach, Scientific Reports, September 2024, Springer Science + Business Media,
DOI: 10.1038/s41598-024-73003-9.
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