What is it about?
Electrical Deep Brain Stimulation (DBS) to a part of the human reward system - the superolateral part of the median forebrain bundle (slMFB) - is efficacious in relieving symptoms of extremely treatment resistant forms of major depression in the majority of patients.
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Why is it important?
Patients who did not experience any benefit from dozens of treatments including psychotherapy, medications and electroconvulsive therapy responded to DBS
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This page is a summary of: Superolateral medial forebrain bundle deep brain stimulation in major depression: a gateway trial, Neuropsychopharmacology, March 2019, Springer Science + Business Media,
DOI: 10.1038/s41386-019-0369-9.
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