What is it about?
Here we study the expression of DNAM-1 on NK cells and DNAM-1 ligands on blasts from AML patients stratified by age.
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Why is it important?
Considering the relevance of DNAM-1 in NK recognition and killing of leukemic cells, the reduced expression of this receptor on NK cells from AML patients can represent an additional mechanism of tumor escape
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This page is a summary of: Decreased expression of DNAM‐1 on NK cells from acute myeloid leukemia patients, Immunology and Cell Biology, March 2011, Wiley,
DOI: 10.1038/icb.2011.15.
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